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Drug Name | GSK343 |
Trade Name | |
Synonyms | GSK-343|GSK 343 |
Drug Descriptions |
GSK343 is an inhibitor of EZH2, which decreases tri-methylation of H3K27, potentially resulting in decreased growth and increased apoptosis of tumor cells (PMID: 23759589, PMID: 31791385). |
DrugClasses | EZH2 inhibitor 20 |
CAS Registry Number | 1346704-33-3 |
NCIT ID | NA |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Dasatinib + GSK343 | Dasatinib GSK343 | 0 | 0 |
GSK343 | GSK343 | 0 | 0 |
GSK343 + MK2206 | GSK343 MK2206 | 0 | 0 |
GSK343 + Selumetinib | GSK343 Selumetinib | 0 | 0 |