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Drug Name | Rigosertib |
Trade Name | |
Synonyms | ON01910 |
Drug Descriptions |
Rigosertib (ON01910) is a small molecule inhibitor of Plk1, resulting in mitotic cell-cycle arrest and inhibition of tumor growth (PMID: 15766665, PMID: 32442785). |
DrugClasses | PLK1 Inhibitor 18 |
CAS Registry Number | 592542-59-1 |
NCIT ID | C152216 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Aldoxorubicin + Rigosertib | Aldoxorubicin Rigosertib | 0 | 0 |
Gemcitabine + Rigosertib | Gemcitabine Rigosertib | 0 | 0 |
Nivolumab + Rigosertib | Nivolumab Rigosertib | 0 | 1 |
Oxaliplatin + Rigosertib | Oxaliplatin Rigosertib | 0 | 0 |
Pembrolizumab + Rigosertib | Pembrolizumab Rigosertib | 0 | 1 |
Rigosertib | Rigosertib | 3 | 1 |
Rigosertib + Trametinib | Rigosertib Trametinib | 0 | 0 |