Rigosertib
Drug Detail
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| Drug Name | Rigosertib |
| Trade Name | |
| Synonyms | ON01910 |
| Drug Descriptions |
Rigosertib (ON01910) is a small molecule inhibitor of Plk1, resulting in mitotic cell-cycle arrest and inhibition of tumor growth (PMID: 15766665, PMID: 32442785). |
| DrugClasses | PLK1 Inhibitor 18 |
| CAS Registry Number | 592542-59-1 |
| NCIT ID | C152216 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Aldoxorubicin + Rigosertib | Aldoxorubicin Rigosertib | 0 | 0 |
| Gemcitabine + Rigosertib | Gemcitabine Rigosertib | 0 | 0 |
| Nivolumab + Rigosertib | Nivolumab Rigosertib | 0 | 1 |
| Oxaliplatin + Rigosertib | Oxaliplatin Rigosertib | 0 | 0 |
| Pembrolizumab + Rigosertib | Pembrolizumab Rigosertib | 0 | 1 |
| Rigosertib | Rigosertib | 3 | 1 |
| Rigosertib + Trametinib | Rigosertib Trametinib | 0 | 0 |
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