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Drug Name | MK-4166 |
Trade Name | |
Synonyms | MK4166|MK 4166 |
Drug Descriptions |
MK-4166 is an activating monoclonal antibody against the glucocorticoid-induced tumor necrosis factor receptor, TNFRSF18 (GITR, CD357), which leads to enhanced cytotoxic immune response against tumor cells (PMID: 28611044). |
DrugClasses | GITR Antibody 7 |
CAS Registry Number | NA |
NCIT ID | C116065 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
MK-4166 | MK-4166 | 0 | 1 |
MK-4166 + Nivolumab | MK-4166 Nivolumab | 0 | 1 |
MK-4166 + Pembrolizumab | MK-4166 Pembrolizumab | 0 | 0 |