MK-4166
Drug Detail
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| Drug Name | MK-4166 |
| Trade Name | |
| Synonyms | MK4166|MK 4166 |
| Drug Descriptions |
MK-4166 is an activating monoclonal antibody against the glucocorticoid-induced tumor necrosis factor receptor, TNFRSF18 (GITR, CD357), which leads to enhanced cytotoxic immune response against tumor cells (PMID: 28611044). |
| DrugClasses | GITR Antibody 7 |
| CAS Registry Number | NA |
| NCIT ID | C116065 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| MK-4166 | MK-4166 | 0 | 1 |
| MK-4166 + Nivolumab | MK-4166 Nivolumab | 0 | 1 |
| MK-4166 + Pembrolizumab | MK-4166 Pembrolizumab | 0 | 0 |
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