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Drug Name | NU6027 |
Trade Name | |
Synonyms | |
Drug Descriptions |
NU6027 is a small molecule inhibitor of ATR and CDK2, which may enhance the sensitivity of chemotherapeutic agents and result in decreased cell survival (PMID: 21730979, PMID: 27355194). |
DrugClasses | ATR Inhibitor 16 CDK2 Inhibitor 31 |
CAS Registry Number | 220036-08-8 |
NCIT ID | NA |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Camptothecin + NU6027 | Camptothecin NU6027 | 0 | 0 |
Cisplatin + NU6027 | Cisplatin NU6027 | 0 | 0 |
Doxorubicin + NU6027 | Doxorubicin NU6027 | 0 | 0 |
Hydroxyurea + NU6027 | Hydroxyurea NU6027 | 0 | 0 |
NU6027 | NU6027 | 0 | 0 |
NU6027 + Rucaparib | NU6027 Rucaparib | 0 | 0 |
NU6027 + Temozolomide | NU6027 Temozolomide | 1 | 0 |