Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@genomenon.com
Drug Name | GSK3052230 |
Trade Name | |
Synonyms | FP-1039|HGS1036|GSK-3052230|GSK 3052230 |
Drug Descriptions |
GSK3052230 (FP-1039) is an FGF ligand trap which prevents FGF1, FGF2, and FGF4 from binding corresponding receptors thereby preventing downstream signaling and activation (PMID: 26078430, PMID: 31065954, PMID: 31446228). |
DrugClasses | |
CAS Registry Number | 1631072-93-9 |
NCIT ID | C77970 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Carboplatin + GSK3052230 + Paclitaxel | Carboplatin GSK3052230 Paclitaxel | 1 | 0 |
Cisplatin + Etoposide + GSK3052230 | Cisplatin Etoposide GSK3052230 | 1 | 0 |
Cisplatin + GSK3052230 + Pemetrexed Disodium | Cisplatin GSK3052230 Pemetrexed Disodium | 0 | 0 |
GSK3052230 | GSK3052230 | 4 | 1 |