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Drug Name | G007-LK |
Trade Name | |
Synonyms | |
Drug Descriptions |
G007-LK inhibits tankyrase, which leads to stabilization of AXIN, thereby resulting in degradation of beta-catenin and decreased growth of APC-deficient tumors (PMID: 23539443, PMID: 32575464). |
DrugClasses | Tankyrase Inhibitor 11 |
CAS Registry Number | 1380672-07-0 |
NCIT ID | NA |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Buparlisib + G007-LK | Buparlisib G007-LK | 1 | 0 |
G007-LK | G007-LK | 35 | 0 |
G007-LK + Imatinib | G007-LK Imatinib | 1 | 0 |
G007-LK + Trametinib | G007-LK Trametinib | 3 | 0 |