Vactosertib
Drug Detail
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| Drug Name | Vactosertib |
| Trade Name | |
| Synonyms | EW-7197|TEW-7197|TEW 7197 |
| Drug Descriptions |
Vactosertib (TEW 7197) is a small molecule that inhibits ALK5, leading to decreased TGF-beta signaling and potentially resulting in decreased tumor cell metastasis (PMID: 24817629, PMID: 31673825) |
| DrugClasses | TGFB inhibitor 5 |
| CAS Registry Number | 1352608-82-2 |
| NCIT ID | C116357 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Aldesleukin + Vactosertib | Aldesleukin Vactosertib | 0 | 1 |
| Durvalumab + Vactosertib | Durvalumab Vactosertib | 0 | 1 |
| Imatinib + Vactosertib | Imatinib Vactosertib | 0 | 0 |
| Paclitaxel + Vactosertib | Paclitaxel Vactosertib | 0 | 0 |
| Pomalidomide + Vactosertib | Pomalidomide Vactosertib | 0 | 1 |
| Vactosertib | Vactosertib | 0 | 5 |
| Vactosertib + VAY736 | VAY736 Vactosertib | 0 | 0 |
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