Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@genomenon.com
Drug Name | Vactosertib |
Trade Name | |
Synonyms | EW-7197|TEW-7197|TEW 7197 |
Drug Descriptions |
Vactosertib (TEW 7197) is a small molecule that inhibits ALK5, leading to decreased TGF-beta signaling and potentially resulting in decreased tumor cell metastasis (PMID: 24817629, PMID: 31673825) |
DrugClasses | TGFB inhibitor 5 |
CAS Registry Number | 1352608-82-2 |
NCIT ID | C116357 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Aldesleukin + Vactosertib | Aldesleukin Vactosertib | 0 | 1 |
Durvalumab + Vactosertib | Durvalumab Vactosertib | 0 | 1 |
Imatinib + Vactosertib | Imatinib Vactosertib | 0 | 0 |
Paclitaxel + Vactosertib | Paclitaxel Vactosertib | 0 | 0 |
Pomalidomide + Vactosertib | Pomalidomide Vactosertib | 0 | 1 |
Vactosertib | Vactosertib | 0 | 4 |
Vactosertib + VAY736 | VAY736 Vactosertib | 0 | 0 |