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Drug Name | Omaveloxolone |
Trade Name | |
Synonyms | RTA 408|RTA-408 |
Drug Descriptions |
Omaveloxolone (RTA 408) is an activator of Nrf2 (NFE2L2) and inhibitor of NF-kappa B, which inhibits tumor growth through regulation of antioxidant and pro-inflammatory gene expression (PMID: 25897966, PMID: 31487581). |
DrugClasses | |
CAS Registry Number | 1474034-05-3 |
NCIT ID | C113443 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Omaveloxolone | Omaveloxolone | 0 | 1 |