Motolimod
Drug Detail
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| Drug Name | Motolimod |
| Trade Name | |
| Synonyms | VTX-2337|VTX-378 |
| Drug Descriptions |
Motolimod (VTX-2337) binds to and activates Toll-like receptor 8 (TLR8), resulting in enhanced antibody-dependent cell-mediated cytotoxicity (PMID: 22128302, PMID: 28453702, PMID: 29931076). |
| DrugClasses | TLR8 Agonist 10 |
| CAS Registry Number | 926927-61-9 |
| NCIT ID | C80521 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Aldoxorubicin + Durvalumab + Motolimod | Aldoxorubicin Durvalumab Motolimod | 0 | 1 |
| Cetuximab + Motolimod | Cetuximab Motolimod | 0 | 0 |
| Cyclophosphamide + Motolimod + Pegfilgrastim | Cyclophosphamide Motolimod Pegfilgrastim | 0 | 1 |
| Motolimod | Motolimod | 0 | 1 |
| Motolimod + Nivolumab | Motolimod Nivolumab | 0 | 2 |
| Motolimod + Pegylated liposomal doxorubicin | Motolimod Pegylated liposomal doxorubicin | 0 | 0 |
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