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Drug Name | Imgatuzumab |
Trade Name | |
Synonyms | RG7160|GA201|RG-7160|GA-201|RO 5083945|RO5083945 |
Drug Descriptions |
Imgatuzumab (RG7160) is a humanized antibody directed against EGFR, which prevents ligand binding and dimerization, resulting in decreased EGFR signaling and increased immune response toward EGFR-expressing tumor cells (PMID: 23209031, PMID: 28950289). |
DrugClasses | EGFR Antibody 60 |
CAS Registry Number | 959963-46-3 |
NCIT ID | C78838 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Imgatuzumab | Imgatuzumab | 0 | 1 |
Imgatuzumab + Irinotecan | Imgatuzumab Irinotecan | 0 | 0 |