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Drug Name FRAX597
Trade Name
Synonyms FRAX-597
Drug Descriptions

FRAX597 is a small-molecule inhibitor of the group I PAKs (PAK1, PAK2, and PAK3), which may result in decreased tumor growth (PMID: 23543898, PMID: 32186433, PMID: 32064922).

DrugClasses PAK1 Inhibitor 11
CAS Registry Number 1286739-19-2
NCIT ID NA

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Therapy Name Drugs Efficacy Evidence Clinical Trials
FRAX597 FRAX597 0 0
FRAX597 + Sotorasib FRAX597 Sotorasib 0 0


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