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| Drug Name | Lumretuzumab |
| Trade Name | |
| Synonyms | RG7116|RO5479599 |
| Drug Descriptions |
Lumretuzumab (RO5479599) is a humanized anti-Her3 (ERBB3) antibody that binds to and inhibits human epidermal growth factor receptor signaling, leading to growth inhibition in tumors (PMID: 26463709, PMID: 31423336). |
| DrugClasses | HER3 (ERBB3) Antibody 28 |
| CAS Registry Number | 1448327-63-6 |
| NCIT ID | C104058 |
| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Carboplatin + Lumretuzumab + Paclitaxel | Carboplatin Lumretuzumab Paclitaxel | 0 | 0 |
| Cetuximab + Lumretuzumab | Cetuximab Lumretuzumab | 0 | 0 |
| Erlotinib + Lumretuzumab | Erlotinib Lumretuzumab | 0 | 0 |
| Lumretuzumab | Lumretuzumab | 0 | 0 |
| Lumretuzumab + Paclitaxel | Lumretuzumab Paclitaxel | 0 | 0 |
| Lumretuzumab + Pertuzumab | Lumretuzumab Pertuzumab | 0 | 0 |