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Drug Name | GLA-SE |
Trade Name | |
Synonyms | G100|TLR-4 agonist G100|glucopyranosyl lipid A stable emulsion |
Drug Descriptions |
GLA-SE is an immune adjuvant that binds to and activates toll-like receptor 4 (TLR4), leading to activation of innate immunity (PMID: 22147791). |
DrugClasses | TLR4 Agonist 2 |
CAS Registry Number | 1246298-63-4 |
NCIT ID | C113649 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Cyclophosphamide + GLA-SE + Pembrolizumab | Cyclophosphamide GLA-SE Pembrolizumab | 0 | 1 |
GLA-SE | GLA-SE | 0 | 1 |
GLA-SE + MART-1 antigen | GLA-SE MART-1 antigen | 0 | 1 |
GLA-SE + Pembrolizumab | GLA-SE Pembrolizumab | 0 | 1 |