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Drug Name | Glembatumumab vedotin |
Trade Name | |
Synonyms | CDX-011 |
Drug Descriptions |
Glembatumumab vedotin (CDX-011) is a conjugate of human anti-glycoprotein NMB (GPNMB) antibody and the cytotoxic agent monomethyl auristatin E (MMAE), which induces cell death in Gpnmb-overexpressing tumor cells (PMID: 25847941, PMID: 31586757). |
DrugClasses | |
CAS Registry Number | 1182215-65-1 |
NCIT ID | C78449 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Glembatumumab vedotin | Glembatumumab vedotin | 0 | 5 |