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Therapy Name | Glembatumumab vedotin |
Synonyms | |
Therapy Description |
Glembatumumab vedotin (CDX-011) is a conjugate of human anti-glycoprotein NMB (GPNMB) antibody and the cytotoxic agent monomethyl auristatin E (MMAE), which induces cell death in Gpnmb-overexpressing tumor cells (PMID: 25847941, PMID: 31586757). |