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Drug Name | EZN-2968 |
Trade Name | |
Synonyms | SPC2968|RO7070179|EZN 2968|EZN2968|SPC 2968|SPC-2968|RO-7070179|RO 7070179 |
Drug Descriptions |
EZN-2968 is an antisense oligonucleotide that hybridizes with hypoxia-inducible factor-1alpha (HIF-1alpha) mRNA and inhibits HIF-1alpha protein expression, leading to tumor growth inhibition (PMID: 18974394, PMID: 25257607). |
DrugClasses | Antisense Therapy 14 |
CAS Registry Number | NA |
NCIT ID | C68930 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
EZN-2968 | EZN-2968 | 0 | 1 |