Custirsen
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| Drug Name | Custirsen |
| Trade Name | |
| Synonyms | Antisense Clusterin|Antisense TRPM-2|OGX-011|CC-8490 |
| Drug Descriptions |
Custirsen (OGX-011) is an antisense oligo targeting clusterin, which leads to apoptosis in tumor cells (PMID: 23130925, PMID: 30732140). |
| DrugClasses | Antisense Therapy 14 |
| CAS Registry Number | 890056-27-6 |
| NCIT ID | C169869 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Carboplatin + Custirsen + Gemcitabine | Carboplatin Custirsen Gemcitabine | 0 | 0 |
| Cisplatin + Custirsen + Gemcitabine | Cisplatin Custirsen Gemcitabine | 0 | 0 |
| Custirsen | Custirsen | 0 | 0 |
| Custirsen + Docetaxel | Custirsen Docetaxel | 0 | 1 |
| Custirsen + Docetaxel + Prednisone | Custirsen Docetaxel Prednisone | 0 | 0 |
| Custirsen + Mitoxantrone + Prednisone | Custirsen Mitoxantrone Prednisone | 0 | 0 |
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