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Drug Name | SEL24-B489 |
Trade Name | |
Synonyms | SEL24|SEL 24|MEN1703|MEN-1703 |
Drug Descriptions |
SEL24-B489 (MEN1703) is an inhibitor of PIM kinases 1, 2, 3, and FLT3, which may suppress cell growth and induce apoptosis (Blood 126 (23):706.December 2015, PMID: 29682194). |
DrugClasses | FLT3 Inhibitor 69 PIM Inhibitor (Pan) 9 |
CAS Registry Number | 1616359-00-2 |
NCIT ID | C133540 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Glofitamab-gxbm + SEL24-B489 | Glofitamab-gxbm SEL24-B489 | 0 | 1 |
Ibrutinib + SEL24-B489 | Ibrutinib SEL24-B489 | 0 | 0 |
SEL24-B489 | SEL24-B489 | 0 | 1 |