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Drug Name | CTX-1 |
Trade Name | |
Synonyms | CTX1 |
Drug Descriptions |
CTX-1 binds to and inhibits Mdm4 (MdmX), which disrupts the interaction between Tp53 and Mdm4, leading to stabilization of Tp53 and potentially leading to increased tumor cell death (PMID: 26883273). |
DrugClasses | MDM4 inhibitor 8 |
CAS Registry Number | 501935-96-2 |
NCIT ID | NA |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
CTX-1 | CTX-1 | 4 | 0 |
CTX-1 + Nutlin-3a | CTX-1 Nutlin-3a | 2 | 0 |