CTX-1
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| Drug Name | CTX-1 |
| Trade Name | |
| Synonyms | CTX1 |
| Drug Descriptions |
CTX-1 binds to and inhibits Mdm4 (MdmX), which disrupts the interaction between Tp53 and Mdm4, leading to stabilization of Tp53 and potentially leading to increased tumor cell death (PMID: 26883273). |
| DrugClasses | MDM4 inhibitor 8 |
| CAS Registry Number | 501935-96-2 |
| NCIT ID | NA |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| CTX-1 | CTX-1 | 4 | 0 |
| CTX-1 + Nutlin-3a | CTX-1 Nutlin-3a | 2 | 0 |
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