rAd-hCD40L
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| Drug Name | rAd-hCD40L |
| Trade Name | |
| Synonyms | rAd.CD40L|ISF35 |
| Drug Descriptions |
rAd-hCD40L is a recombinant adenovirus vector expressing human CD40LG (CD40L), which activates TNFRSF5 (CD40) signaling and leads to apoptosis and growth inhibition in tumor cells (PMID: 19461675). |
| DrugClasses | |
| CAS Registry Number | NA |
| NCIT ID | C2493 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Pembrolizumab + rAd-hCD40L | Pembrolizumab rAd-hCD40L | 0 | 1 |
| rAd-hCD40L | rAd-hCD40L | 0 | 0 |
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