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| Drug Name | BMS-986178 |
| Trade Name | |
| Synonyms | BMS986178|BMS 986178 |
| Drug Descriptions |
BMS-986178 is an activating monoclonal antibody to TNFRSF4 (OX40, CD134), which mimics the binding of the ligand, TNFSF4 (OX40L, CD252), to stimulate proliferation of T-cells and enhance an anti-tumor response (PMID: 33148673). |
| DrugClasses | OX40 Antibody 15 |
| CAS Registry Number | NA |
| NCIT ID | C128026 |
| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| BMS-986178 | BMS-986178 | 0 | 1 |
| BMS-986178 + Ipilimumab | BMS-986178 Ipilimumab | 0 | 0 |
| BMS-986178 + Ipilimumab + Nivolumab | BMS-986178 Ipilimumab Nivolumab | 0 | 0 |
| BMS-986178 + Nelitolimod | BMS-986178 Nelitolimod | 0 | 2 |
| BMS-986178 + Nivolumab | BMS-986178 Nivolumab | 0 | 0 |