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Drug Name | BMS-986178 |
Trade Name | |
Synonyms | BMS986178|BMS 986178 |
Drug Descriptions |
BMS-986178 is an activating monoclonal antibody to TNFRSF4 (OX40, CD134), which mimics the binding of the ligand, TNFSF4 (OX40L, CD252), to stimulate proliferation of T-cells and enhance an anti-tumor response (PMID: 33148673). |
DrugClasses | OX40 Antibody 14 |
CAS Registry Number | NA |
NCIT ID | C128026 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
BMS-986178 | BMS-986178 | 0 | 1 |
BMS-986178 + Ipilimumab | BMS-986178 Ipilimumab | 0 | 0 |
BMS-986178 + Ipilimumab + Nivolumab | BMS-986178 Ipilimumab Nivolumab | 0 | 0 |
BMS-986178 + Nivolumab | BMS-986178 Nivolumab | 0 | 0 |
BMS-986178 + SD-101 | BMS-986178 SD-101 | 0 | 2 |