RG7386
Drug Detail
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| Drug Name | RG7386 |
| Trade Name | |
| Synonyms | RO6874813|RG 7386|RG-7386 |
| Drug Descriptions |
RO6874813 (RG7386) is a bispecific antibody that binds TNFRSF10B (DR5) on tumor cells and fibroblast-activation protein (FAP) found on fibroblasts in the tumor stroma to induce apoptosis (PMID: 27037412). |
| DrugClasses | |
| CAS Registry Number | NA |
| NCIT ID | NA |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Doxorubicin + RG7386 | Doxorubicin RG7386 | 0 | 0 |
| Irinotecan + RG7386 | Irinotecan RG7386 | 0 | 0 |
| RG7386 | RG7386 | 0 | 1 |
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