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Drug Name | IMO-2125 |
Trade Name | |
Synonyms | Tilsotolimod |
Drug Descriptions |
Tilsotolimod (IMO-2125) is an immunomodulatory oligonucleotide (IMO) that targets toll-like receptor 9 (TLR9), resulting in activation of anti-tumor immunity (PMID: 23207140, PMID: 29956749). |
DrugClasses | TLR9 Agonist 9 |
CAS Registry Number | 2089768-67-0 |
NCIT ID | C125080 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
ABBV-368 + Budigalimab + IMO-2125 + Nab-paclitaxel | ABBV-368 Budigalimab IMO-2125 Nab-paclitaxel | 0 | 1 |
ABBV-368 + IMO-2125 | ABBV-368 IMO-2125 | 0 | 1 |
ABBV-368 + IMO-2125 + Nab-paclitaxel | ABBV-368 IMO-2125 Nab-paclitaxel | 0 | 1 |
IMO-2125 | IMO-2125 | 0 | 2 |
IMO-2125 + Ipilimumab | IMO-2125 Ipilimumab | 0 | 2 |
IMO-2125 + Ipilimumab + Nivolumab | IMO-2125 Ipilimumab Nivolumab | 0 | 2 |
IMO-2125 + Nivolumab | IMO-2125 Nivolumab | 0 | 1 |
IMO-2125 + Pembrolizumab | IMO-2125 Pembrolizumab | 0 | 1 |