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Drug Name ALKS 4230
Trade Name
Synonyms RDB 1450|Nemvaleukin alfa|ALKS-4230|ALKS4230|RBD1450|RBD-1450
Drug Descriptions

ALKS 4230 is a fusion protein of IL2 and IL2RA, which activates effector lymphocytes upon binding to intermediate affinity IL2 receptors to enhance cell death of tumor cells (AACR; Cancer Res 2017;77(13 Suppl):Abstract nr 4088, PMID: 32317293).

DrugClasses
CAS Registry Number 2315268-27-8
NCIT ID C128107

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Therapy Name Drugs Efficacy Evidence Clinical Trials
ALKS 4230 ALKS 4230 0 5
ALKS 4230 + Pembrolizumab ALKS 4230 Pembrolizumab 0 4


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