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Drug Name | Sotevtamab |
Trade Name | |
Synonyms | AB 16B5|AB16B5|AB-16B5 |
Drug Descriptions |
Sotevtamab is a monoclonal antibody that inhibits the activity of tumor associated human clusterin (sCLU), potentially decreasing epithelial-to-mesenchymal transition and reducing tumor growth (J Clin Oncol 42, 2024 (suppl 16; abstr 8577)). |
DrugClasses | |
CAS Registry Number | NA |
NCIT ID | C121778 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Docetaxel + Sotevtamab | Docetaxel Sotevtamab | 0 | 1 |
Fluorouracil + Leucovorin + Oxaliplatin + Sotevtamab | Fluorouracil Leucovorin Oxaliplatin Sotevtamab | 0 | 1 |
Sotevtamab | Sotevtamab | 0 | 1 |