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Drug Name | Taletrectinib |
Trade Name | |
Synonyms | DS6051b|DS-6051B|DS-6051|AB-106 |
Drug Descriptions |
Taletrectinib (DS6051b) is an inhibitor of NTRK1/2/3 and ROS1 fusion proteins, which blocks downstream signaling and may lead to inhibition of tumor cell growth (PMID: 32591465). |
DrugClasses | ROS1 Inhibitor 20 Trk Receptor Inhibitor (Pan) 32 |
CAS Registry Number | 1505515-69-4 |
NCIT ID | C118948 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
SHP099 + Taletrectinib | SHP099 Taletrectinib | 0 | 0 |
Taletrectinib | Taletrectinib | 6 | 3 |