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Drug Name | SHP099 |
Trade Name | |
Synonyms | SHP-099|SHP 099 |
Drug Descriptions |
SHP099 is an allosteric inhibitor of SHP2 that stabilizes SHP2 in its autoinhibited conformation, which reduces downstream signaling and potentially leads to decreased growth of receptor tyrosine kinase-driven tumors (PMID: 27362227, PMID: 31043123). |
DrugClasses | SHP2 Inhibitor 20 |
CAS Registry Number | 1801747-42-4 |
NCIT ID | NA |