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Drug Name | Cofetuzumab pelidotin |
Trade Name | |
Synonyms | h6M24-vc0101|PTK7-targeted antibody-drug conjugate|ABBV-647|PF-06647020 |
Drug Descriptions |
Cofetuzumab pelidotin (PF-06647020) is an antibody-drug conjugate comprising a monoclonal antibody against PTK7 linked to Aur0101, which delivers the cytotoxic agent to PTK7-expressing tumor cells, leading to cell death (PMID: 28077676). |
DrugClasses | |
CAS Registry Number | 1869937-48-3 |
NCIT ID | C123828 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Avelumab + Cofetuzumab pelidotin | Avelumab Cofetuzumab pelidotin | 0 | 1 |
Cofetuzumab pelidotin | Cofetuzumab pelidotin | 0 | 2 |
Cofetuzumab pelidotin + Gedatolisib | Cofetuzumab pelidotin Gedatolisib | 0 | 1 |