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| Drug Name | Avelumab |
| Trade Name | Bavencio |
| Synonyms | MSB0010718C |
| Drug Descriptions |
Bavencio (avelumab) is a monoclonal antibody binds to human immunosuppressive ligand programmed death-ligand 1 (PD-L1, CD274) and blocks protein signaling, resulting in immune regulation and antitumor immunity (PMID: 26014098). Bavencio (avelumab) is FDA-approved for use in adult and pediatric patients of 12 years or older with metastatic Merkel cell carcinoma, as maintenance therapy in locally advanced or metastatic urothelial carcinoma (UC), in locally advanced or metastatic UC that progressed following chemotherapy, and in combination with axitinib as first-line therapy in advanced renal cell carcinoma (FDA.gov). |
| DrugClasses | Immune Checkpoint Inhibitor 149 PD-L1/PD-1 antibody 121 |
| CAS Registry Number | 1537032-82-8 |
| NCIT ID | C116870 |
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