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Drug Name | Buthionine sulfoximine |
Trade Name | |
Synonyms | BSO |
Drug Descriptions |
Buthionine sulfoximine (BSO) is a GSH synthesis inhibitor, which results in increased reactive oxygen species, thereby possibly leading to apoptotic and/or cytotoxic activity (PMID: 17991446, PMID: 27092812). |
DrugClasses | |
CAS Registry Number | 5072-26-4 |
NCIT ID | C1029 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Buthionine sulfoximine | Buthionine sulfoximine | 1 | 0 |
Buthionine sulfoximine + Radiotherapy | Buthionine sulfoximine Radiotherapy | 1 | 0 |
Buthionine sulfoximine + Sirolimus | Buthionine sulfoximine Sirolimus | 0 | 0 |