Buthionine sulfoximine
Drug Detail
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| Drug Name | Buthionine sulfoximine |
| Trade Name | |
| Synonyms | BSO |
| Drug Descriptions |
Buthionine sulfoximine (BSO) is a GSH synthesis inhibitor, which results in increased reactive oxygen species, thereby possibly leading to apoptotic and/or cytotoxic activity (PMID: 17991446, PMID: 27092812). |
| DrugClasses | |
| CAS Registry Number | 5072-26-4 |
| NCIT ID | C1029 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Buthionine sulfoximine | Buthionine sulfoximine | 0 | 0 |
| Buthionine sulfoximine + Radiotherapy | Buthionine sulfoximine Radiotherapy | 0 | 0 |
| Buthionine sulfoximine + Sirolimus | Buthionine sulfoximine Sirolimus | 1 | 0 |
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