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Drug Name | A-dmDT390-bisFv(UCHT1) |
Trade Name | |
Synonyms | anti-T cell immunotoxin A-dmDT390-bisFv(UCHT1)|Resimmune |
Drug Descriptions |
Resimmune (A-dmDT390-bisFv(UCHT1)) comprises the diphtheria toxin catalytic and translocation domains fused to antibody fragments that target the CD3-epsilon component of the T-cell receptor, potentially resulting in increased death of CD3-epsilon expressing tumor cells (PMID: 25795722) |
DrugClasses | |
CAS Registry Number | 1470038-56-2 |
NCIT ID | C74004 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
A-dmDT390-bisFv(UCHT1) | A-dmDT390-bisFv(UCHT1) | 0 | 0 |
A-dmDT390-bisFv(UCHT1) + Pembrolizumab | A-dmDT390-bisFv(UCHT1) Pembrolizumab | 0 | 1 |