GSK3174998
Drug Detail
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| Drug Name | GSK3174998 |
| Trade Name | |
| Synonyms | GSK-3174998|GSK 3174998 |
| Drug Descriptions |
GSK3174998 is an activating monoclonal antibody to TNFRSF4 (OX40, CD134), which mimics the binding of the ligand, TNFSF4 (OX40L, CD252), to stimulate proliferation of T-cells and enhance an anti-tumor response (Cancer Res July 15 2016 (76) (14 Supplement) CT027). |
| DrugClasses | OX40 Antibody 15 |
| CAS Registry Number | 2089398-68-3 |
| NCIT ID | C124783 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Belantamab mafodotin-blmf + GSK3174998 | Belantamab mafodotin-blmf GSK3174998 | 0 | 1 |
| GSK1795091 + GSK3174998 | GSK1795091 GSK3174998 | 0 | 1 |
| GSK3174998 | GSK3174998 | 0 | 2 |
| GSK3174998 + Pembrolizumab | GSK3174998 Pembrolizumab | 0 | 0 |
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