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Drug Name ARQ 531
Trade Name
Synonyms ARQ531|ARQ-531|Nemtabrutinib|MK-1026|MK 1026|MK1026
Drug Descriptions

ARQ 531 is an ATP-competitive BTK inhibitor with activity against wild-type BTK and BTK C481S, which may inhibit migration and viability of tumor cells (PMID: 30093506, PMID: 31992353).

DrugClasses BTK inhibitor 37
CAS Registry Number 2095393-15-8
NCIT ID C138066

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Therapy Name Drugs Efficacy Evidence Clinical Trials
ARQ 531 ARQ 531 1 4
ARQ 531 + Rituximab ARQ 531 Rituximab 0 1
ARQ 531 + Venetoclax ARQ 531 Venetoclax 0 1
ARQ 531 + VLS-101 ARQ 531 VLS-101 0 1


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