Drug Detail
Contact
Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@genomenon.com
| Drug Name | ARQ 531 |
| Trade Name | |
| Synonyms | ARQ531|ARQ-531|Nemtabrutinib|MK-1026|MK 1026|MK1026 |
| Drug Descriptions |
ARQ 531 is an ATP-competitive BTK inhibitor with activity against wild-type BTK and BTK C481S, which may inhibit migration and viability of tumor cells (PMID: 30093506, PMID: 31992353). |
| DrugClasses | BTK inhibitor 38 |
| CAS Registry Number | 2095393-15-8 |
| NCIT ID | C138066 |
Filtering
- Case insensitive filtering will display rows if any text in any cell matches the filter term
- Use simple literal full or partial string matches
- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
- Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
Sorting
- Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
- Click on any column header arrows to sort by that column
- Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.
| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| ARQ 531 | ARQ 531 | 1 | 4 |
| ARQ 531 + Pembrolizumab | ARQ 531 Pembrolizumab | 0 | 1 |
| ARQ 531 + Rituximab | ARQ 531 Rituximab | 0 | 1 |
| ARQ 531 + Venetoclax | ARQ 531 Venetoclax | 0 | 1 |
| ARQ 531 + VLS-101 | ARQ 531 VLS-101 | 0 | 1 |
CKB BOOST