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Drug Name | Denileukin diftitox |
Trade Name | Ontak |
Synonyms | DAB389IL2|DAB389-IL2|LY335348|DAB389 interleukin-2 |
Drug Descriptions |
Ontak (denileukin diftitox) is an interleukin-2 (IL-2) recombinant fusion protein comprised of the IL-2 protein and the diptheria toxin, and may potentially inhibit the growth and survival of tumor cells expressing the IL-2 receptor (PMID: 11707818, PMID: 27737881). |
DrugClasses | |
CAS Registry Number | 173146-27-5 |
NCIT ID | C1476 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Denileukin diftitox | Denileukin diftitox | 0 | 1 |
Denileukin diftitox + Sirolimus | Denileukin diftitox Sirolimus | 0 | 0 |
Denileukin diftitox + Temsirolimus | Denileukin diftitox Temsirolimus | 0 | 0 |