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Drug Name | Ulevostinag |
Trade Name | |
Synonyms | MK 1454|MK-1454 |
Drug Descriptions |
Ulevostinag (MK-1454) is an agonist of the stimulator of interferon genes protein (TMEM173, STING1), that when activated leads to the release of cytokines that stimulate cytotoxic T lymphocytes to enhance the anti-tumor immune response (Ann Oncol, Oct 2018, 29 (suppl 8), abstract LBA15, PMID: 31355488). |
DrugClasses | STING1 Agonist 19 |
CAS Registry Number | NA |
NCIT ID | C132258 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Pembrolizumab + Ulevostinag | Pembrolizumab Ulevostinag | 0 | 2 |
Ulevostinag | Ulevostinag | 0 | 1 |