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Drug Name | Unesbulin |
Trade Name | |
Synonyms | PTC596|PTC-596|PTC 596 |
Drug Descriptions |
Unesbulin (PTC596) inhibits BMI-1, which may result in mitochondrial apoptosis in cancer cells (PMID: 28211885, PMID: 32232850, PMID: 38684039). |
DrugClasses | |
CAS Registry Number | 1610964-64-1 |
NCIT ID | C121645 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Carboplatin + Paclitaxel + Unesbulin | Carboplatin Paclitaxel Unesbulin | 0 | 1 |
Dacarbazine + Unesbulin | Dacarbazine Unesbulin | 0 | 1 |
Unesbulin | Unesbulin | 0 | 2 |