Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@genomenon.com
| Drug Name | Unesbulin |
| Trade Name | |
| Synonyms | PTC596|PTC-596|PTC 596 |
| Drug Descriptions |
Unesbulin (PTC596) inhibits BMI-1, which may result in mitochondrial apoptosis in cancer cells (PMID: 28211885, PMID: 32232850, PMID: 38684039). |
| DrugClasses | |
| CAS Registry Number | 1610964-64-1 |
| NCIT ID | C121645 |
| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Carboplatin + Paclitaxel + Unesbulin | Carboplatin Paclitaxel Unesbulin | 0 | 1 |
| Dacarbazine + Unesbulin | Dacarbazine Unesbulin | 0 | 1 |
| Unesbulin | Unesbulin | 0 | 2 |