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Drug Name Dacarbazine
Trade Name Deticene
Synonyms Biocarbazine R
Drug Descriptions

Deticene (dacarbazine) alkylates and cross-links DNA, which disrupts the cell-cycle. Dacarbazine is FDA approved for melanoma (FDA.gov).

DrugClasses Chemotherapy - Alkylating 18
CAS Registry Number 4342-03-4
NCIT ID C411

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Bleomycin + Brentuximab vedotin + Dacarbazine + Doxorubicin + Nivolumab + Vinblastine Bleomycin Brentuximab vedotin Dacarbazine Doxorubicin Nivolumab Vinblastine 0 1
Bleomycin + Dacarbazine + Doxorubicin + Nivolumab + Vinblastine Bleomycin Dacarbazine Doxorubicin Nivolumab Vinblastine 0 1
Bleomycin + Dacarbazine + Doxorubicin + Pembrolizumab + Vinblastine Bleomycin Dacarbazine Doxorubicin Pembrolizumab Vinblastine 0 1
Bleomycin + Dacarbazine + Doxorubicin + Vinblastine Bleomycin Dacarbazine Doxorubicin Vinblastine 0 3
Brentuximab vedotin + Cyclophosphamide + Dacarbazine + Dexamethasone + Doxorubicin + Etoposide Brentuximab vedotin Cyclophosphamide Dacarbazine Dexamethasone Doxorubicin Etoposide 0 1
Brentuximab vedotin + Cyclophosphamide + Dacarbazine + Doxorubicin + Etoposide + Prednisone Brentuximab vedotin Cyclophosphamide Dacarbazine Doxorubicin Etoposide Prednisone 0 0
Brentuximab vedotin + Dacarbazine Brentuximab vedotin Dacarbazine 0 1
Brentuximab vedotin + Dacarbazine + Doxorubicin + Filgrastim + Vinblastine Brentuximab vedotin Dacarbazine Doxorubicin Filgrastim Vinblastine 0 2
Brentuximab vedotin + Dacarbazine + Doxorubicin + Nivolumab Brentuximab vedotin Dacarbazine Doxorubicin Nivolumab 0 1
Brentuximab vedotin + Dacarbazine + Doxorubicin + Nivolumab + Rituximab + Vinblastine Brentuximab vedotin Dacarbazine Doxorubicin Nivolumab Rituximab Vinblastine 0 1
Brentuximab vedotin + Dacarbazine + Doxorubicin + Nivolumab + Vinblastine Brentuximab vedotin Dacarbazine Doxorubicin Nivolumab Vinblastine 0 2
Brentuximab vedotin + Dacarbazine + Doxorubicin + Pembrolizumab Brentuximab vedotin Dacarbazine Doxorubicin Pembrolizumab 0 1
Brentuximab vedotin + Dacarbazine + Doxorubicin + Rituximab + Vinblastine Brentuximab vedotin Dacarbazine Doxorubicin Rituximab Vinblastine 0 1
Brentuximab vedotin + Dacarbazine + Doxorubicin + Vinblastine Brentuximab vedotin Dacarbazine Doxorubicin Vinblastine 0 4
Dacarbazine Dacarbazine 0 14
Dacarbazine + Dinutuximab beta + Doxorubicin + Ifosfamide + Vincristine Sulfate Dacarbazine Dinutuximab beta Doxorubicin Ifosfamide Vincristine Sulfate 0 1
Dacarbazine + Doxorubicin Dacarbazine Doxorubicin 0 1
Dacarbazine + Doxorubicin + Ifosfamide + Vincristine Sulfate Dacarbazine Doxorubicin Ifosfamide Vincristine Sulfate 0 1
Dacarbazine + Doxorubicin + Nivolumab + Vinblastine Dacarbazine Doxorubicin Nivolumab Vinblastine 0 2
Dacarbazine + Doxorubicin + Pembrolizumab + Vinblastine Dacarbazine Doxorubicin Pembrolizumab Vinblastine 0 4
Dacarbazine + Doxorubicin + Tislelizumab + Vinblastine Dacarbazine Doxorubicin Tislelizumab Vinblastine 0 1
Dacarbazine + Doxorubicin + Vinblastine Dacarbazine Doxorubicin Vinblastine 0 2
Dacarbazine + Gemcitabine + Trabectedin Dacarbazine Gemcitabine Trabectedin 0 1
Dacarbazine + Onfekafusp alfa Dacarbazine Onfekafusp alfa 0 1
Dacarbazine + Ramucirumab Dacarbazine Ramucirumab 0 0
Dacarbazine + Selumetinib Dacarbazine Selumetinib 0 1
Dacarbazine + Unesbulin Dacarbazine Unesbulin 0 1


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