Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@genomenon.com
Drug Name | Preladenant |
Trade Name | |
Synonyms | MK-3814|SCH420814 |
Drug Descriptions |
Preladenant (MK-3814) binds to and inhibits the adenosine A2A (ADORA2A) receptor on immune cells, resulting in activation of an anti-tumor immune response by blocking binding of the immunosuppressive metabolite, adenosine (PMID: 22676397, PMID: 19109019). |
DrugClasses | Adenosine Targeting 23 |
CAS Registry Number | 377727-87-2 |
NCIT ID | C76394 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Pembrolizumab + Preladenant | Pembrolizumab Preladenant | 0 | 1 |
Preladenant | Preladenant | 0 | 1 |