RXDX-106
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| Drug Name | RXDX-106 |
| Trade Name | |
| Synonyms | CEP-40783|CEP40783|CEP 40783|RXDX106|RXDX 106 |
| Drug Descriptions |
RXDX-106 (CEP-40783) is a small molecule inhibitor of TAM family kinases (Axl, Mertk, and Tyro3) and Met that promotes anti-tumor immune response, resulting in tumor growth inhibition (Eur J Cancer, Vol 69, Supplement 1, December 2016, Page S31, PMID: 30501104, PMID: 30723115). |
| DrugClasses | AXL Inhibitor 30 MERTK Inhibitor 13 MET Inhibitor 59 TYRO3 Inhibitor 7 |
| CAS Registry Number | 1437321-24-8 |
| NCIT ID | C150585 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| RXDX-106 | RXDX-106 | 0 | 0 |
| RXDX-106 + unspecified PD-1 antibody | RXDX-106 unspecified PD-1 antibody | 0 | 0 |
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