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Drug Name | RXDX-106 |
Trade Name | |
Synonyms | CEP-40783|CEP40783|CEP 40783|RXDX106|RXDX 106 |
Drug Descriptions |
RXDX-106 (CEP-40783) is a small molecule inhibitor of TAM family kinases (Axl, Mertk, and Tyro3) and Met that promotes anti-tumor immune response, resulting in tumor growth inhibition (Eur J Cancer, Vol 69, Supplement 1, December 2016, Page S31, PMID: 30501104, PMID: 30723115). |
DrugClasses | AXL Inhibitor 30 MERTK Inhibitor 13 MET Inhibitor 59 TYRO3 Inhibitor 8 |
CAS Registry Number | 1437321-24-8 |
NCIT ID | C150585 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
RXDX-106 | RXDX-106 | 0 | 0 |
RXDX-106 + unspecified PD-1 antibody | RXDX-106 unspecified PD-1 antibody | 0 | 0 |