MVT-5873
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| Drug Name | MVT-5873 |
| Trade Name | |
| Synonyms | HuMab 5B1|HuMab-5B1|BNT321 |
| Drug Descriptions |
MVT-5873 (HuMab-5B1) is an IgG1 antibody that binds to the sialyl Lewis A epitope of CA19-9, which may result in antitumor activity including tumor growth inhibition (Cancer Res 2016;76(24 Suppl):Abstract nr A73, PMID: 32399263). |
| DrugClasses | |
| CAS Registry Number | 2101410-19-7 |
| NCIT ID | C125900 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Fluorouracil + Irinotecan + Leucovorin + MVT-5873 + Oxaliplatin | Fluorouracil Irinotecan Leucovorin MVT-5873 Oxaliplatin | 0 | 1 |
| Gemcitabine + MVT-5873 + Nab-paclitaxel | Gemcitabine MVT-5873 Nab-paclitaxel | 0 | 0 |
| MVT-1075 + MVT-5873 | MVT-1075 MVT-5873 | 0 | 1 |
| MVT-5873 | MVT-5873 | 0 | 2 |
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