LY3295668
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| Drug Name | LY3295668 |
| Trade Name | |
| Synonyms | LY3295668 erbumine|AK-01|AK 01|LY-3295668|LY 3295668 |
| Drug Descriptions |
LY3295668 selectively inhibits Aurora A kinase (AURKA), potentially resulting in increased apoptosis and decreased proliferation of tumor cells, and inhibition of tumor growth (PMID: 31530649). |
| DrugClasses | Aurka Inhibitors 27 |
| CAS Registry Number | 1919888-06-4 |
| NCIT ID | C148501 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Cyclophosphamide + LY3295668 + Topotecan | Cyclophosphamide LY3295668 Topotecan | 0 | 1 |
| LY3295668 | LY3295668 | 1 | 4 |
| LY3295668 + LY3537982 | LY3295668 LY3537982 | 0 | 1 |
| LY3295668 + Midazolam | LY3295668 Midazolam | 0 | 1 |
| LY3295668 + Osimertinib | LY3295668 Osimertinib | 0 | 1 |
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