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Drug Name | LY3295668 |
Trade Name | |
Synonyms | LY3295668 erbumine|AK-01 |
Drug Descriptions |
LY3295668 selectively inhibits Aurora A kinase (AURA), which results in apoptosis, inhibition of cell proliferation, and tumor growth inhibition (PMID: 31530649). |
DrugClasses | Aurka Inhibitors 27 |
CAS Registry Number | 1919888-06-4 |
NCIT ID | C148501 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Cyclophosphamide + LY3295668 + Topotecan | Cyclophosphamide LY3295668 Topotecan | 0 | 1 |
LY3295668 | LY3295668 | 1 | 4 |
LY3295668 + LY3537982 | LY3295668 LY3537982 | 0 | 1 |
LY3295668 + Midazolam | LY3295668 Midazolam | 0 | 1 |
LY3295668 + Osimertinib | LY3295668 Osimertinib | 0 | 1 |