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Drug Name LY3537982
Trade Name
Synonyms LY 3537982|LY-3537982|Olomorasib
Drug Descriptions

LY3537982 selectively inhibits KRAS G12C, potentially leading to growth inhibition of KRAS G12C-expressing tumor cells (Cancer Res 2021;81(13_Suppl):Abstract nr 1259).

DrugClasses KRAS G12C inhibitor 34
CAS Registry Number 2771246-13-8
NCIT ID C181751

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Abemaciclib + LY3537982 Abemaciclib LY3537982 0 1
Carboplatin + LY3537982 + Pembrolizumab + Pemetrexed Disodium Carboplatin LY3537982 Pembrolizumab Pemetrexed Disodium 0 1
Cetuximab + LY3537982 Cetuximab LY3537982 0 1
Cisplatin + LY3537982 + Pembrolizumab + Pemetrexed Disodium Cisplatin LY3537982 Pembrolizumab Pemetrexed Disodium 0 1
Erlotinib + LY3537982 Erlotinib LY3537982 0 1
LY3214996 + LY3537982 LY3214996 LY3537982 0 1
LY3295668 + LY3537982 LY3295668 LY3537982 0 1
LY3537982 LY3537982 0 1
LY3537982 + Pembrolizumab LY3537982 Pembrolizumab 0 1
LY3537982 + Sintilimab LY3537982 Sintilimab 0 1


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