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Drug Detail
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| Drug Name | ABBV-621 |
| Trade Name | |
| Synonyms | ABBV621|ABBV 621|eftozanermin alfa|APG880|eftoza |
| Drug Descriptions |
ABBV-621 (eftozanermin alfa) is TRAIL receptor agonist comprising human IgG1-Fc fused to the TRAIL-receptor binding domain, which potentially induces apoptosis and decreases tumor growth (PMID: 35467243, PMID: 33687950). |
| DrugClasses | |
| CAS Registry Number | 1820660-69-2 |
| NCIT ID | C146854 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| ABBV-621 | ABBV-621 | 0 | 1 |
| ABBV-621 + Bortezomib + Dexamethasone | ABBV-621 Bortezomib Dexamethasone | 0 | 1 |
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