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Drug Name | ABBV-621 |
Trade Name | |
Synonyms | ABBV621|ABBV 621|eftozanermin alfa|APG880|eftoza |
Drug Descriptions |
ABBV-621 (eftozanermin alfa) is TRAIL receptor agonist comprising human IgG1-Fc fused to the TRAIL-receptor binding domain, which potentially induces apoptosis and decreases tumor growth (PMID: 35467243, PMID: 33687950). |
DrugClasses | |
CAS Registry Number | 1820660-69-2 |
NCIT ID | C146854 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
ABBV-621 | ABBV-621 | 0 | 1 |
ABBV-621 + Bortezomib + Dexamethasone | ABBV-621 Bortezomib Dexamethasone | 0 | 1 |