TRC102
Drug Detail
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| Drug Name | TRC102 |
| Trade Name | |
| Synonyms | Methoxyamine|TRC-102 |
| Drug Descriptions |
TRC102 (Methoxyamine) inhibits the base excision repair pathway, potentially resulting in increased sensitivity to chemotherapeutic agents and anti-tumor activity (J Clin Oncol 34, 2016 (suppl; abstr 2556), PMID: 23054206, PMID: 32556884). |
| DrugClasses | |
| CAS Registry Number | 67-62-9 |
| NCIT ID | C78084 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Carboplatin + Durvalumab + Pemetrexed Disodium + TRC102 | Carboplatin Durvalumab Pemetrexed Disodium TRC102 | 0 | 1 |
| Cisplatin + Durvalumab + Pemetrexed Disodium + TRC102 | Cisplatin Durvalumab Pemetrexed Disodium TRC102 | 0 | 1 |
| Temozolomide + TRC102 | TRC102 Temozolomide | 0 | 1 |
| TRC102 | TRC102 | 0 | 0 |
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