Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@genomenon.com
Drug Name | TRC102 |
Trade Name | |
Synonyms | Methoxyamine|TRC-102 |
Drug Descriptions |
TRC102 (Methoxyamine) inhibits the base excision repair pathway, potentially resulting in increased sensitivity to chemotherapeutic agents and anti-tumor activity (J Clin Oncol 34, 2016 (suppl; abstr 2556), PMID: 23054206, PMID: 32556884). |
DrugClasses | |
CAS Registry Number | 67-62-9 |
NCIT ID | C78084 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Cisplatin + Durvalumab + Pemetrexed Disodium + TRC102 | Cisplatin Durvalumab Pemetrexed Disodium TRC102 | 0 | 1 |
Temozolomide + TRC102 | TRC102 Temozolomide | 0 | 1 |
TRC102 | TRC102 | 0 | 0 |