SEA-CD40
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| Drug Name | SEA-CD40 |
| Trade Name | |
| Synonyms | SEACD40|SEA CD40|Cifurtilimab |
| Drug Descriptions |
SEA-CD40 is an agonistic monoclonal antibody that targets TNFRSF5 (CD40), potentially resulting in activation of T-cells and enhanced anti-tumor immune response (Cancer Res 2015;75(15 Suppl), Abstract nr 2472). |
| DrugClasses | CD40 Antibody 16 |
| CAS Registry Number | 1629760-27-5 |
| NCIT ID | C121217 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Carboplatin + Pembrolizumab + Pemetrexed Disodium + SEA-CD40 | Carboplatin Pembrolizumab Pemetrexed Disodium SEA-CD40 | 0 | 1 |
| Gemcitabine + Nab-paclitaxel + Pembrolizumab + SEA-CD40 | Gemcitabine Nab-paclitaxel Pembrolizumab SEA-CD40 | 0 | 0 |
| Pembrolizumab + SEA-CD40 | Pembrolizumab SEA-CD40 | 0 | 2 |
| SEA-CD40 | SEA-CD40 | 0 | 1 |
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