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Drug Name | SAR439459 |
Trade Name | |
Synonyms | SAR-439459|SAR 439459 |
Drug Descriptions |
SAR439459 is a monoclonal antibody that targets transforming growth factor beta 1 (TGFB1, TGFbeta), which may lead to tumor regression in combination with PD-1 (PDCD1) immune checkpoint inhibitors (AACR; Cancer Res 2018;78(13 Suppl):Abstract nr 2790). |
DrugClasses | TGFB (Pan) Antibody 5 |
CAS Registry Number | NA |
NCIT ID | C146862 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Atezolizumab + Bevacizumab + SAR439459 | Atezolizumab Bevacizumab SAR439459 | 0 | 0 |
Cemiplimab + SAR439459 | Cemiplimab SAR439459 | 0 | 2 |
Dexamethasone + Isatuximab + SAR439459 | Dexamethasone Isatuximab SAR439459 | 0 | 1 |
SAR439459 | SAR439459 | 0 | 1 |