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| Drug Name | Isatuximab |
| Trade Name | Sarclisa |
| Synonyms | SAR650984|isatuximab-irfc |
| Drug Descriptions |
Sarclisa (isatuximab-irfc) is a humanized monoclonal antibody against CD38 that induces anti-tumor immune reaction against CD38-positive tumor cells (PMID: 24987056). Sarclisa (isatuximab-irfc) in combination with Pomalyst (pomalidomide) and dexamethasone is FDA approved for use in patients with multiple myeloma who have received two or more prior therapies, in combination with Kyprolis (carfilzomib) and dexamethasone for patients with relapsed or refractory multiple myeloma who have received one to three prior lines of therapy, and in combination with Velcade (bortezomib), Revlimid (lenalidomide), and dexamethasone for patients with newly diagnosed multiple myeloma ineligible for transplant (FDA.gov). |
| DrugClasses | CD38 Antibody 20 |
| CAS Registry Number | 1461640-62-9 |
| NCIT ID | C90578 |
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