Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@genomenon.com
Drug Name | Rivogenlecleucel |
Trade Name | |
Synonyms | BPX-501|BPX501|BPX 501 |
Drug Descriptions |
Rivogenlecleucel (BPX-501) comprises allogeneic T-cells transduced with a vector encoding inducible Casp9 that is linked to a drug binding domain, which enables induction of Casp9 with AP1903 if GVHD develops, resulting increased Casp9 expression and induction of T-cell death (PMID: 29343836). |
DrugClasses | |
CAS Registry Number | NA |
NCIT ID | C105395 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Rimiducid + Rivogenlecleucel | Rimiducid Rivogenlecleucel | 0 | 2 |
Rivogenlecleucel | Rivogenlecleucel | 0 | 5 |