Rivogenlecleucel
Drug Detail
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| Drug Name | Rivogenlecleucel |
| Trade Name | |
| Synonyms | BPX-501|BPX501|BPX 501 |
| Drug Descriptions |
Rivogenlecleucel (BPX-501) comprises allogeneic T-cells transduced with a vector encoding inducible Casp9 that is linked to a drug binding domain, which enables induction of Casp9 with AP1903 if GVHD develops, resulting increased Casp9 expression and induction of T-cell death (PMID: 29343836). |
| DrugClasses | |
| CAS Registry Number | NA |
| NCIT ID | C105395 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Rimiducid + Rivogenlecleucel | Rimiducid Rivogenlecleucel | 0 | 2 |
| Rivogenlecleucel | Rivogenlecleucel | 0 | 5 |
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