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Drug Name | Rimiducid |
Trade Name | |
Synonyms | AP1903|AP-1903|AP 1903 |
Drug Descriptions |
Rimiducid (AP1903) is a small molecule that selectively binds to mutant FKBP12 and induces dimerization and downstream signaling, which can be used to activate a safety switch in transplanted cells to potentially induce apoptosis and prevent graft-versus-host disease (PMID: 9724721, PMID: 22047558, PMID: 28697888). |
DrugClasses | |
CAS Registry Number | 195514-63-7 |
NCIT ID | C82412 |